Therapeutic Potential of Vagus Nerve Stimulation for Inflammatory Bowel Diseases. Citation: (Bonaz 2021)

A review of the potential of vagus nerve stimulation (VNS) for inflammatory bowel disease (IBD), concludes that targeting the anti-inflammatory properties of the vagus nerve with VNS could be of interest in the management of patients with IBD involving the digestive tract through a non-drug therapy. About 1.5 million Americans and 2.2 million people in Europe are affected by IBD. There is a rising incidence of IBD in Western countries, supporting the hypothesis that “Westernization” of our li...


Review of Transcutaneous Vagus Nerve Stimulation: Challenges for Translation to Clinical Practice. Citation: (Yap 2020)

Several studies investigating the use of transcutaneous vagus nerve stimulation (tVNS) for disorders tinnitus, migraine and pain show therapeutic effects similar to those produced by the more invasive direct vagus nerve stimulation (VNS). Although VNS is an FDA-approved therapy for the treatment of both depression and epilepsy, it is limited to being a second or third-line treatment option for severe, intervention-resistant cases, due to risks involved with device implantation. In contrast, t...